Fulminant hepatic failure in primary dengue infection.
نویسندگان
چکیده
A 9-month-old child presented with four days fever and altered sensorium for 2 days. He developed seizures in the emergency department and was in a state of shock. His blood sugar was 9 mg/dL. He was resuscitated with intravenous fluids. The child had fever, altered sensorium and erythematous skin. His liver was palpable 4 cm below right costal margin and spleen was just palpable. The limbs were spastic and deep tender reflexes were brisk. His initial blood count showed a total count of 23.1 × 103/μL, hematocrit of 33%, platelet count of 22,000/μL. His liver function test were SGPT of 5907 U/L, SGOT of 20,480 U/L and serum bilirubin of 2.7 mg/dL. His prothrombin time was prolonged(68s). Serology for hepatitis A, C and E, and HBs Ag were negative. Imaging showed right sided pleural effusion and moderate ascites. Dengue IgM antibodies were positive and dengue IgG was negative, suggestive of primary dengue infection. He developed progressive jaundice with the maximum bilirubin level of 22.9 mg/ dL, which resolved completely 8 weeks after onset.
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ورودعنوان ژورنال:
- Indian pediatrics
دوره 47 3 شماره
صفحات -
تاریخ انتشار 2010